I used to own a cat (psychotic thing) & never had a problem. The cat wouldn't bother about what was in the enclosure & would only occasionaly sit & look & my snake (which was massive) didn't even look at the cat, even when he was a little kitten. You shoudn't have a problem, but I would highly recommend washing your hands before handling the snake or cleaning the enclosure, if you've been handling the cats, for hygeines sake.